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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e644a194fd8d287bf8091f992c2aa83e05bbd02aedcd40b9605e27d4c92b5723' 
  AND token = 'tjCPAzeKbu/9MGHF9fC9DDgZhj710XyQkD8787f9SXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}