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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c9f4f62c70eba284ba41422d4cf8638933bdb3291f7e3bd0011f3a103ecf715' 
  AND token = '995/I+WxmZzccDKnGmwleTlV34htS4js2NlX70yzieo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}