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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '56416eebcbeb771e82672b81fdadf5de737c36429ecc091646d1f6e147a7e6f8' 
  AND token = 'Vz7RpZcQAtrFH8mWtYpUmKbsVIuPk5CP9qIkYGmm4kk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}