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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bee870f386a0a49802c897ab252cde23736481dde5c1a55b48def0e542642153' 
  AND token = 'R5N1ENE+ycPJDUpshyGypDe23qmW3HXYOlyao2ItfNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}