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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73cddd5c872fc3d7cf22f362c97a5f8910b93a46aacdbed913663a5c757950e7' 
  AND token = 'l9/KZv4CnkrXpvTMk4aPXfO/q07W1uIYrbBp2XEcX6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}