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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a741aefc143b4df1870f67ae9ed5488a4befd55826b9a6bbe13705e1016e5956' 
  AND token = 'nsYm8Wgxg9Nv2jSemfYekNjQZR8VPhBrO1ffqrjiY/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}