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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce8e8d0a292234e76a7d582f024edb7dbd61051c2f78295158da81be259bb4b7' 
  AND token = 'Xw28H8SVSKAAOI8kQUEmBLWuSsm1CTjaKvt1mKTk6cQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}