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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f0ccbe68fb454d060024916a5a610bd3963aafa7477a9d7352fbb0eff4908ba' 
  AND token = 'J+Ox7S9y+tBekkxjUmwWS64Ta8TZjdFkLJ8RQYhSfyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}