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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b29fae03beffad68f2b6ca607a35e44e7230c0abc78ce5f531a6371d91314f0' 
  AND token = 'l6F0Rol5B6s3oAwdM8TQ+BnyBJj1J2ITf0UdOEvbGy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}