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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9900f7a28366379b531076f9d9dde922a7cb61fda11f2e173e6ee147939dfef8' 
  AND token = 'uggQsx0E8NLo/3fIc0npHeRQWnBoeTySKcJw0ObUWlI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}