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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2e84bcd6077e1584d86375f3dd5f9c10561151362e3f52956067b444337937c' 
  AND token = '5/drZLG2dU9B7v40CuGbs5LbpOq0vx3YhHzx/NfPB4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}