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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9728ed730c9cf683c64d354b6e7b0a526f2ec4ef57d030bb9a5ebade4379b12' 
  AND token = '9Dl8RRmR9qw1gjsOMyzhhKMn38Tn05FSfKK0u5V7MVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}