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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd21b1c09d97c2c438fdb40b5233fa043083bea5567f4d2d3c72aa045124d4bfe' 
  AND token = '7EjW172hxVnPvdV8ynpkBHW0G04DBioMNdMNXDf30FM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}