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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20ef163baf4b4f0e9a75bbcbffde07f70cd60287ab34d08259e94385c7c27920' 
  AND token = '1gLBd5nyRR3K/UAsd5NlRmbjdUAAn+wxcbs7H+on+6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}