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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '606e23b0ca44e0b6fc63897b3ba1b1f1c6cf8d87b9dfe52e6021c82397a17c27' 
  AND token = '9fL8WXd4Z3FTGzioG/cjdDp9FaPtK+YuMY8Yn4yF0MI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}