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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7108871f9b28dfe732c4f6aaaae9d8a842e63ca179d3590e4f21c55bc0075ad6' 
  AND token = 'ZxZPNQGNnPdt3mdHuBsK8ASLzzmGRRbo3q1miacF7xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}