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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cf7e6254a0e40d9c721fa29ccc143484c3744b6be1811946bdaff3cac3ed821' 
  AND token = 'fv172KzLPaZ/RIhekkf/FDFaQo6NSJBtIrZdRc1tHIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}