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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5eb6132975eb4163ac1b71251807a65f1ffb74086dbbd75c959eb55338c9506e' 
  AND token = 'ZuUxHElx1w0jv2XIthi2Xb2o0Q6wXNb63Fk1RizUgg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}