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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2584a3ff6f209ae3681f896232730930d0f1f772dff6f3196b859d207f3e4681' 
  AND token = 'fDnWjGODyUIr3sWJZcfx/P8CEViWxxDSxdBUsMCIvJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}