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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a81b73a3ae07ad047366606046d245689f658ef8cf1128fba95063e3b60d49e0' 
  AND token = 'HiqrvJM8XFp1mOyHPZHvkCi6UB0YBmALDF1ixoD7xhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}