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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0951b9f65a57b30df348f940dd3793cca40bde0f7459218b0600d93527c8c8b2' 
  AND token = 'aLoFOnSFdLDkX+eMOX1kdSLoA7tHhjVNcrMV6mPO9Dk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}