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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '327cf65846183c6eedd7e6814da6774fe0923d962d91b47e4dd4ad9ed3ed8b73' 
  AND token = 'kTT32hZTqDhbDrZw6jaCKbux0/g1RfXvw+8ATm2Ydgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}