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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f46595abce3d59f74469ed1551c0f815c50464057f14e37f4a3f1f878d88729' 
  AND token = '4eOqV+k+JSGLMo57+kI7LG1l1ROOxy3fM1SsMobqLkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}