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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7406bb43b881ad331f55fb5f1f5606e7b3668255c2e0f747cd0a43e71936490d' 
  AND token = 'z7LWeQ+pbU1CfVeVB+KkfDdbDcUL5jBnMvNv3wJcJBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}