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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '316972ba00c55bb43d09fa687cb5cefd0b02c6e55b6f4dce1fe0bc53d16a780b' 
  AND token = 'MEYlXSUhtfpBcWy/+5en8SBEAz9rE6yNa4t+xhj39mE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}