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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f26b43e442258a3c0cf1835d436363edf880b83e75f3d1df74db85d0ab2c6aa4' 
  AND token = '8FlHszNRw0loOQXaYBJeNcb0OkHwbY9Zzj69Qtju/nA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}