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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3e0b9a1afc2a9e0bbd49b8670142b36c2474222a121a00e3f01029a3e99fe8c' 
  AND token = 'pUIRRFJ+4N5Sy3hVR2dKm31FUI3pFe80nGGat3v7IyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}