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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e18bd66af64a1ddda02c40a17c3f0e13d2fe15195c06c50ef0a40974bb152e2' 
  AND token = 'vK5IpOdh+ltKHgvemdapa3LGgvjZECOGx/0tzc9Buu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}