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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39df8816979729826ef4b5e4857a142f1a3eb5c4efa1410c22af4a2f42b0e590' 
  AND token = 'SdCTM9kTFeQ6MpVdDr9zESnfb3avncpegmD66pQqUjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}