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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1df436e93e570c50e8c0fe8161cda0fe8e1df2fe2fab9f71155ff273663e6189' 
  AND token = '+EXEOaNoC6bBSnsxfY42kGXrRJw/wQf9FqBZAsAMx+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}