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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a4265cd27d8020460fc50d8bc3e81b8d1863d77dd5a09e5a9485ed2e91709c3' 
  AND token = 'Hz5/VYFdLZrvLve022odzrRacF2acfJmDAMt3DekaFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}