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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '075b892ab15fad8bc4cf2b972a91394df4fe6619662c1fa4b292d5d3b351705a' 
  AND token = '9tlLh+S4XnsSQkBblL5OCWTpc23h9c9wrVY6G30tFWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}