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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c509222a00c7dc75e5675f7b45dd9753e7eb5f10f20630677fbc1b04b59e7923' 
  AND token = 'kY3qkKOfXVLJFSv9Apz/rLIEc5ybT9ktStNejCXzaOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}