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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc8968f1b411aba48f844809a129e178040809f461b769926abb767161c41657' 
  AND token = '6lWkLreY7pWboUHxa/6np1jng2q21qTtrToYb7T/VLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}