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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f4b641a03b0f1ff5d20e6e3613c11ce35ec3b70df346bf57fbb2a5f38143f87' 
  AND token = 'zYa6sRgOS7olGJETMz4kPjsLWnKAkwkVzlX+W+W0xIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}