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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3bc46e64c7b8c52841e171a239d9c082a734b09d94ae4e4a943a8bba0751b65' 
  AND token = 'iTfyBOM6qu0GLkxg6dwTbl83DB69XUnJOgQwZ1+FXb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}