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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3fbcfcb84477f53f71aeb8abeaf2afd3f2214124e12aa33d7f96143b68f7eb7' 
  AND token = 'H2g5uUWt48Zjq1c1+LLjz2+UpVacC/23t4LTc6z4LRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}