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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a62adece0120e75c29f02b62a4d1a1f2222f7f1a545fa666a7e0e588333a4400' 
  AND token = 'Ho1Sjmnas2HwiNDp2nqgnNjNzm4HqT6mXLA6QkGILxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}