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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49d60545e114aaeb4a3b52a1976224f17a0cf9546ac7e62a8ad650ce65fda258' 
  AND token = '+sH9zbZqUA3o3dZCuz6a3+jP9+a8IrAFfXBxfy31K7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}