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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5f7280b4a70e7be670e001e44f8e083a72718da1c14e8bb0a167c3c4e63fcd5' 
  AND token = 'l+QR1eHvTUHJbOvdIteloMMRJlCqk4V1LE194vYxYlk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}