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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c514f46999f39de20d869b7802b3d2158c2a9678380910d96bf94531a5fa646' 
  AND token = 'tFPH7bIP7Y5v+78+oV7p6aDbeCLbqZUpv7576Nfba5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}