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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '177ee967b5b0be788472ddd980c5b9db1b0346ff91c0242db9761a126c33826f' 
  AND token = 'fuwyk7JJvaefMCrdVYlRoCE2D87jclh7mvB05+yP6tE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}