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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f7d25fe8039c9164b9e71c5d3d01fbe3678de4880f38fc433c2fdf9b5d85d5b' 
  AND token = 'dGyE48MU+6rePWUdGmCFpqTYoWxbHN+G0eBKAO4x9CY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}