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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b11b735540909998ca9b632dfc07aa349510b1c4e12b04ceb89fc0c6f58de105' 
  AND token = 'efUG3gC7hQDP9+ula1hxkdVL064kF6LvWVCG/HNBZVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}