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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '94a7c812c49ab40c9a6982d51d8d5cbda7f97cc354aed8c9f0cc3a1abdb3c073' 
  AND token = '2yTcg/jRsrwWH2uRrssZSX+p2gm4KUhdRToz4JUiep4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}