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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e754b1b89a63cd4b83436ea48e6654efe398e9a4eef35fb3eae5c9ed052b2ed' 
  AND token = 'mQLIBGKQEEW+H9UC69nw/GIddf0xdYW3cgnjN9mBw1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}