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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce56c8be870fc830f52f28bff3fbf42c88dc5eaf165242bd511911f56bae0e0c' 
  AND token = 'AlZ/hNVy8/c8zrqG/7iy4UmDRt92F3PjkzjFxjFzeZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}