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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47e16f9710bc7273a9be788777896494902ed3865c7c780e455dc47bfb1416ff' 
  AND token = '32NHXTyUpBkeEBJVLHCp7fUBvPxL/4ZBkO4qMQEJ/3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}