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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb437435fffe9501628dc51dcf01849d81ff4c8eb5a6b5028371080229f8d5d4' 
  AND token = 'DQzD825TLFGmGFbiK5MLcclW8fvUZ06wpgQ71qz4qB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}