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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a1918b47129b7146936371969a5e2936dfa1a9d83c73e7253f685d5d24d5a7d' 
  AND token = 'FiggyEzotMpgGx1favVyrMXsmXa+khknXS0XsUAhefQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}